BOTOX Cosmetic Botulinum Toxin Type A
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BOTOX® Cosmetic 10-minute Treatment— A Quick Tour
Announcing the first and only FDA-approved treatment indicated for the temporary improvement in the appearance of moderate to severe glabellar (frown) lines associated with corrugator and/or procerus muscle activity in adult patients aged 65 years or less.1

  1. Response within days, results that can last up to 4 months1,2
  2. High rates of improvement, assessed by physicians1,2
  3. Patients reported high rates of improvement in the appearance of glabellar lines1,2

How glabellar lines are formed
Glabellar lines are the dynamic wrinkles between the brows caused by the contraction of corrugator and/or procerus muscles.

Movement of corrugator and procerus muscles can cause the skin between the brows to crease. As skin becomes less elastic over time, repeated contraction of these muscles may create visible lines and wrinkles.

BOTOX® Cosmetic works on the muscles that cause glabellar lines
BOTOX® Cosmetic is injected directly into the corrugator and procerus muscles, where it enters the nerve endings to block the release of acetylcholine, the chemical that causes muscles to contract. Once the muscles are at rest, skin becomes smoother.

Results you can see...
In a clinical study (N=537) with BOTOX® Cosmetic (n=405), the majority of patients (82.5%) reported an improvement in glabellar lines after a week. Results were still visible up to 4 months later.1,2

*Unretouched clinical photos taken while frowning before and 30 days after treatment with BOTOX® Cosmetic.

Individual results may vary.

Since the procedure is nonsurgical, no recovery time is needed.

Performed in the office, the simple procedure takes about 10 minutes.

1. BOTOX® Cosmetic [package insert]. Irvine, Calif: Allergan, Inc; 2002.
2. Data on file, Allergan.

BOTOX® Cosmetic is indicated for the temporary improvement in the appearance of moderate to severe glabellar lines associated with corrugator and/or procerus muscle activity in patients 18 to 65 years of age.

Important Safety Information

BOTOX® Cosmetic is contraindicated in the presence of infection at the proposed injection site(s) and in individuals with known hypersensitivity to any ingredient in the formulation. There have been rare reports of adverse events involving the cardiovascular system. Serious and/or immediate hypersensitivity reactions have been reported rarely. These reactions include anaphylaxis, urticaria, soft-tissue edema, and dyspnea.

The most common adverse events following injection include blepharoptosis and nausea. Localized pain, infection, inflammation, tenderness, swelling, erythema and/or bleeding/bruising may be associated with the injection. Patients with neuromuscular disorders such as ALS, myasthenia gravis, or Lambert-Eaton syndrome may be at increased risk of serious adverse events.

Please see the additional safety information and full prescribing information.

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